Details for gene set NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy.phenotype_wtNotch_versus_normalThy.cls #wtNotch_versus_normalThy_repos
Phenotype	phenotype_wtNotch_versus_normalThy.cls#wtNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_SIGNALING EVENTS REGULATED BY RET TYROSINE KINASE
Enrichment Score (ES)	-0.6724089
Normalized Enrichment Score (NES)	-1.5301639
Nominal p-value	0.009456265
FDR q-value	0.25282994
FWER p-Value	0.958

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	PTK2	1780148	780	0.874	-0.0015	No
2	CYLD	6590079	1543	0.439	-0.0222	No
3	GRB2	6650398	1561	0.435	-0.0029	No
4	BCL3	3990440	1936	0.326	-0.0080	No
5	HRAS	1980551	2087	0.286	-0.0028	No
6	UBE2D3	3190452	2324	0.231	-0.0048	No
7	NFKB1	5420358	2339	0.229	0.0051	No
8	PDLIM7	4780136	3035	0.127	-0.0265	No
9	PXN	3290048 6400132	3201	0.111	-0.0302	No
10	TNF	6650603	3230	0.108	-0.0267	No
11	RAC1	4810687	3573	0.080	-0.0414	No
12	MALT1	4670292	3761	0.066	-0.0484	No
13	PRKCA	6400551	3810	0.064	-0.0481	No
14	REL	360707	3994	0.055	-0.0554	No
15	BIRC2	2940435 4730020	4458	0.039	-0.0786	No
16	SOS1	7050338	4675	0.034	-0.0887	No
17	DOK6	4850673	4947	0.028	-0.1019	No
18	RASA1	1240315	4972	0.028	-0.1019	No
19	RIPK2	5050072 6290632	5362	0.023	-0.1219	No
20	CREB1	1500717 2230358 3610600 6550601	5622	0.020	-0.1349	No
21	ATM	3610110 4050524	6095	0.015	-0.1596	No
22	DOK5	770113 3450156	6264	0.014	-0.1680	No
23	PIK3R1	4730671	7181	0.009	-0.2170	No
24	RAN	2260446 4590647	7473	0.008	-0.2323	No
25	DOK1	1050279 2680112 5220273	7620	0.007	-0.2399	No
26	XPO1	540707	8292	0.005	-0.2758	No
27	BCAR1	1340215	8752	0.003	-0.3004	No
28	PTPN11	2230100 2470180 6100528	9170	0.002	-0.3228	No
29	NCK1	6200575 6510050	9651	0.000	-0.3487	No
30	ARRB2	2060441	9730	-0.000	-0.3529	No
31	PIK3CA	6220129	9883	-0.001	-0.3611	No
32	GDNF	4050487 5720739	10796	-0.003	-0.4101	No
33	SRC	580132	11138	-0.004	-0.4283	No
34	RAP1A	1090025	11438	-0.006	-0.4441	No
35	NOD2	2510050	11439	-0.006	-0.4439	No
36	FBXW11	6450632	11943	-0.008	-0.4706	No
37	IRS1	1190204	12178	-0.009	-0.4828	No
38	GRB10	6980082	12405	-0.010	-0.4946	No
39	CHUK	7050736	12475	-0.010	-0.4978	No
40	RET	3850746	13211	-0.015	-0.5367	No
41	SYK	6940133	13759	-0.022	-0.5652	No
42	SHC1	2900731 3170504 6520537	14167	-0.028	-0.5858	No
43	JUN	840170	14517	-0.036	-0.6030	No
44	ERC1	1580170 2630717 6110762 6840280	14833	-0.047	-0.6178	No
45	MAPK1	3190193 6200253	14896	-0.050	-0.6188	No
46	SHANK3	4070348 5420451	15280	-0.072	-0.6361	No
47	IKBKG	3450092 3840377 6590592	15354	-0.077	-0.6365	No
48	IKBKB	6840072	15396	-0.080	-0.6350	No
49	GFRA1	3610152	15534	-0.093	-0.6381	No
50	DOK4	4060452	15555	-0.095	-0.6348	No
51	MAPK3	580161 4780035	16052	-0.154	-0.6544	No
52	MAPK8	2640195	16060	-0.156	-0.6475	No
53	GRB7	2100471	16166	-0.173	-0.6452	No
54	CRK	1230162 4780128	16356	-0.203	-0.6459	No
55	NFKB2	2320670	16848	-0.300	-0.6585	Yes
56	MAPK14	5290731	16936	-0.320	-0.6483	Yes
57	RELA	3830075	16981	-0.335	-0.6351	Yes
58	RELB	1400048	17053	-0.356	-0.6224	Yes
59	TRAF6	4810292 6200132	17300	-0.454	-0.6146	Yes
60	LCK	3360142	17374	-0.493	-0.5957	Yes
61	MAP3K14	5890435	17378	-0.493	-0.5729	Yes
62	GAB1	2970156	17684	-0.634	-0.5599	Yes
63	BCL10	2360397	17750	-0.680	-0.5318	Yes
64	NFKBIA	1570152	17914	-0.797	-0.5036	Yes
65	TNFAIP3	2900142	18472	-2.065	-0.4378	Yes
66	TNFRSF1A	1090390 6520735	18601	-3.812	-0.2677	Yes
67	RHOA	580142 5900131 5340450	18614	-5.784	0.0001	Yes